Breakthrough in child cancer research

Researchers have reached a breakthrough in cancer studies after using novel technology to reveal the different genetic patterns of neuroblastoma, an aggressive form of childhood cancer.

Two research teams led by professors Tommy Martinsson, of the Sahlgrenska Academy at the University of Gothenburg, Sweden and Per Kogner of Karolinska Institutet monitored children with neuroblastoma, a nerve cell cancer that has defects in certain chromosomes, for over 20 years.

Helena Car a researcher at the Department of Clinical Genetics at the Sahlgrenska Academy, said: "We found that the children who develop this type of neuroblastoma are twice as old at the onset of the disease as children who develop other types of neuroblastoma. This type progresses more slowly and is more difficult to treat.

Boffins were able to successfully analyse the DNA of tumour cells and identify chromosomal defects with the use of latest genetic techniques, enabling the identification of sub-groups of the most aggressive neuroblastomas.